Fired at the muzzle, a representative .45 ACP load (14.9 g, FMJ, 260 m/s) reaches roughly 12 mm (0.5 inches) into polycarbonate. That is enough to defeat a typical barrier of this material — treat anything behind it as exposed.
About Polycarbonate
A polycarbonate pane (~12 mm); true bullet-resistant glass is far thicker and layered.